Results for 'Thomas Bl Kirkwood'

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  1.  24
    The free‐radical theory of ageing – older, wiser and still alive.Thomas Bl Kirkwood & Axel Kowald - 2012 - Bioessays 34 (8):692-700.
    The continuing viability of the free‐radical theory of ageing has been questioned following apparently incompatible recent results. We show by modelling positional effects of the generation and primary targets of reactive oxygen species that many of the apparently negative results are likely to be misleading. We conclude that there is instead a need to look more closely at the mechanisms by which free radicals contribute to age‐related dysfunction in living systems. There also needs to be deeper understanding of the dynamics (...)
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  2.  21
    Human senescence.Thomas B. L. Kirkwood - 1996 - Bioessays 18 (12):1009-1016.
    Human life expectancy has increased dramatically through improvements in public health, housing, nutrition and general living standards. Lifespan is now limited chiefly by intrinsic senescence and its associated frailty and diseases. Understanding the biological basis of the ageing process is a major scientific challenge that will require integration of molecular, cellular, genetic and physiological approaches. This article reviews progress that has been made to date, particularly with regard to the genetic contribution to senescence and longevity, and assesses the scale of (...)
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  3.  16
    P53 and Ageing: Too Much of a Good Thing?Thomas B. L. Kirkwood - 2002 - Bioessays 24 (7):577-579.
    A recent report by Tyner et al.1 suggests that p53 is bad for longevity. Heterozygotic mice carrying a p53 mutation that apparently enhances the stability of the wild‐type protein showed shorter lifespans and faster ageing while also developing fewer tumours. This fits with the idea that cellular ageing is the price paid for better protection against unlimited proliferation of cancer cells. But other work shows that there is a strong positive association between DNA repair‐mediated protection against cancer and ageing. So (...)
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  4.  5
    The Genetics of Old Age.Thomas B. L. Kirkwood - 2004 - In Justine Burley & John Harris (eds.), A Companion to Genethics. Oxford, UK: Blackwell. pp. 43–50.
    The prelims comprise: Introduction Genetic Architecture of the Life Span Genetics of Longevity Genetics and the Future of Old Age Conclusion.
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  5.  39
    Evolution of the human menopause.Daryl P. Shanley & Thomas B. L. Kirkwood - 2001 - Bioessays 23 (3):282-287.
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  6.  14
    Book review: Becoming immortal: Combining cloning and stem‐cell therapy. [REVIEW]Thomas B. L. Kirkwood - 2004 - Bioessays 26 (1):106-107.
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  7.  24
    Increasing longevity: an important question, a dubious answer. The evolution of death: Why we are living longer. (2006). By Stanley Shostak. State University of New York Press, Albany 246 pp. ISBN: 07914694689. [REVIEW]Thomas B. L. Kirkwood - 2007 - Bioessays 29 (7):710-711.
  8.  15
    Mitochondria and ageing: winning and losing in the numbers game.João F. Passos, Thomas von Zglinicki & Thomas B. L. Kirkwood - 2007 - Bioessays 29 (9):908-917.
    Mitochondrial dysfunction has long been considered a key mechanism in the ageing process but surprisingly little attention has been paid to the impact of mitochondrial number or density within cells. Recent reports suggest a positive association between mitochondrial density, energy homeostasis and longevity. However, mitochondrial number also determines the number of sites generating reactive oxygen species (ROS) and we suggest that the links between mitochondrial density and ageing are more complex, potentially acting in both directions. The idea that increased density, (...)
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  9.  3
    Biology of ageing.Olivier Toussaint, José Remacle, Brian F. C. Clark, Efstathios S. Gonos, Claudio Franceschi & Thomas B. L. Kirkwood - 2000 - Bioessays 22 (10):954-956.
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  10.  5
    Even when no one is looking: fundamental questions of ethical education.Jan Hábl - 2018 - Eugene, Oregon: Cascade Books.
    This book is not a list or an overview of various theories of ethics. Nor is it a didactic manual for specific teaching units on moral education aimed at some group based on age or a particular theme (although some educational frameworks will be proposed). As the title suggests, the book intends to seek the starting points or foundations without which no moral education would be possible. The goal is to formulate and tackle the key questions that precede all moral (...)
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  11.  45
    A Way to Interpret Łukasiewicz Logic and Basic Logic.Thomas Vetterlein - 2008 - Studia Logica 90 (3):407-423.
    Fuzzy logics are in most cases based on an ad-hoc decision about the interpretation of the conjunction. If they are useful or not can typically be found out only by testing them with example data. Why we should use a specific fuzzy logic can in general not be made plausible. Since the difficulties arise from the use of additional, unmotivated structure with which the set of truth values is endowed, the only way to base fuzzy logics on firm ground is (...)
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  12.  16
    Shaping Knowledge about American Labor: External Advising at the U.S. Bureau of Labor Statistics in the Twentieth Century.Thomas A. Stapleford - 2010 - Science in Context 23 (2):187-220.
    ArgumentCreated in 1884, the U.S. Bureau of Labor Statistics has been the major federal source for data in the United States on labor-related topics such as prices, unemployment, compensation, productivity, and family expenditures. This essay traces the development and transformation of formal and informal consulting relationships between the BLS and external groups over the twentieth century. Though such a history cannot, of course, provide a comprehensive analysis of how political values have shaped the construction of labor statistics during this period, (...)
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  13.  28
    The Long‐term Unemployed: A New Protected Class of Employee?Thomas A. Hemphill, Waheeda Lillevik & Francine Cullari - 2012 - Business and Society Review 117 (4):535-553.
    Since the onset of the latest United States (U.S.) recession (beginning in December 2007), the U.S. economy has been posting high unemployment levels consistently exceeding 8 percent. Of specific interest, the U.S. Department of Labor, Bureau of Labor Statistics (BLS), reports on a specific subset of the U.S. unemployed: the long‐term unemployed, defined as those who are unemployed for 27 weeks and over. Since December 2009, the share of the long‐term unemployed of the total U.S. unemployed has exceeded 40 percent (...)
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  14.  12
    Frances McSparran, ed., Octovian Imperator, ed. from MS BL Cotton Caligula A II. Heidelberg: Carl Winter, 1979. Paper. Pp. 123. DM 38. [REVIEW]Thomas J. Heffernan - 1981 - Speculum 56 (2):458.
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  15.  77
    Residuated lattices arising from equivalence relations on Boolean and Brouwerian algebras.Thomas Vetterlein - 2008 - Mathematical Logic Quarterly 54 (4):350-367.
    Logics designed to deal with vague statements typically allow algebraic semantics such that propositions are interpreted by elements of residuated lattices. The structure of these algebras is in general still unknown, and in the cases that a detailed description is available, to understand its significance for logics can be difficult. So the question seems interesting under which circumstances residuated lattices arise from simpler algebras in some natural way. A possible construction is described in this paper.Namely, we consider pairs consisting of (...)
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  16.  40
    Domestic Religious Themes in Pompeian Painting Thomas Fröhlich: Lararien- und Fassadenbilder in den Vesuvstädten: Untersuchungen zur 'volkstümlichen' pompejanischen Malerei. (Mitteilungen des Deutschen Archäologischen Instituts. Römische Abteilung, Ergänzungsheft 32.) Pp. 370; 11 text-figs., 23 colour pls, 41 bl. and w. pls. Mainz: Von Zabern, 1991. DM 198. [REVIEW]Roger Ling - 1993 - The Classical Review 43 (01):139-141.
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  17.  44
    Alzheimer's Disease, Mild Cognitive Impairment, and the Biology of Intrinsic Aging.T. B. L. Kirkwood - 2006 - Philosophy, Psychiatry, and Psychology 13 (1):79-82.
    In lieu of an abstract, here is a brief excerpt of the content:Alzheimer's Disease, Mild Cognitive Impairment, and the Biology of Intrinsic AgingThomas B. L. Kirkwood (bio)Keywordsaging, Alzheimer’s disease, genetic mutation, mild cognitive impairment, telomereThe article by Gaines and Whitehouse (2006) raises key questions about the uncertain relationship between (i) the intrinsic, "normal" aging process, and (ii) the clinicopathologic states represented by the labels of Alzheimer's disease (AD) and mild cognitive impairment (MCI). This short commentary offers a perspective on (...)
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  18.  2
    Demokrits Atome: e. Unters. zur Überlieferung u. zu einigen wichtigen Lehrstücken in Demokrits Physik.Rudolf Löbl - 1976 - Bonn: Habelt.
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  19.  17
    Thomas Scott of Canterbury (1566–1635): Patriot, civic radical, puritan.Cesare Cuttica - 2008 - History of European Ideas 34 (4):475-489.
    This article sheds new light on the interesting but little-studied figure of Thomas Scott of Canterbury (1566–1635). In presenting Scott's ideas I will modify the interpretation laid out by Peter Clark whose groundbreaking study, ‘Thomas Scott and the Growth of Urban Opposition to the Early Stuart Regime’, is still the only secondary source that pays detailed attention to Scott and his thought, especially his religious opinions. The necessity to revisit Clark's interpretation of Scott's place within the political and (...)
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  20.  10
    'Die aufgeregte Gesellschaft: wie Emotionen unsere Moral pragen und die Polarisierung verstarken.Philipp Hübl - 2020 - Bonn: Bundeszentrale für Politische Bildung.
  21. Psychical research and the question of ultimate reality and meaning.Bl Stafford - 1984 - Ultimate Reality and Meaning 7 (1):21-33.
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  22.  87
    Conscience and conscientious objection of health care professionals refocusing the issue.Natasha T. Morton & Kenneth W. Kirkwood - 2009 - HEC Forum 21 (4):351-364.
    Conscience and Conscientious Objection of Health Care Professionals Refocusing the Issue Content Type Journal Article Pages 351-364 DOI 10.1007/s10730-009-9113-x Authors Natasha T. Morton, The University of Western Ontario Ontario Canada N6A 5B9 Kenneth W. Kirkwood, Arthur and Sonia Labatt Health Sciences Building London Ontario Canada N6A 5B9 Journal HEC Forum Online ISSN 1572-8498 Print ISSN 0956-2737 Journal Volume Volume 21 Journal Issue Volume 21, Number 4.
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  23.  6
    On being human(e): Comenius' pedagogical humanization as an anthropological problem.Jan Hábl - 2017 - Eugene, Oregon: Pickwick Publications. Edited by Jerry Root.
    There is a difference between that which is and that which is to be. Anthropologically: there is a way I am, and the way I am to be, or not to be. How are we to explain this? This book presents the argument that human nature is both complex and complicated in at least two specific ways--ontologically and ethically. In our being we are indisputably good, dignified, worthy, important, or even noble. But in our morality we are ambivalent--capable of both (...)
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  24.  2
    Restoration of human affairs: utopianism or realism?Jan Hábl, Mária Potočárová, Peter Cimala & Pavel Černý (eds.) - 2022 - Eugene, Oregon: Pickwick Publications.
    The aim of this book is to explore the possibilities and limits of Comenius's greatest and most important work, General Consultation Concerning Restoration of Human Affairs. The humanity of people is not quite right, but not quite lost--that is the foundational anthropological assumption of the Consultation. How does Comenius understand humanity? What are human affairs? What's wrong with them? And the most important question: Can they be somehow corrected, improved, or restored?
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  25.  5
    Utopismus, nebo realismus Komenského projektu nápravy věcí lidských?Jan Hábl (ed.) - 2019 - Červený Kostelec: Pavel Mervart.
  26.  4
    Der Untergrund des Denkens: eine Philosophie des Unbewussten.Philipp Hübl - 2015 - Reinbek: Rowohlt.
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  27. Social Learning Strategies in Networked Groups.Thomas N. Wisdom, Xianfeng Song & Robert L. Goldstone - 2013 - Cognitive Science 37 (8):1383-1425.
    When making decisions, humans can observe many kinds of information about others' activities, but their effects on performance are not well understood. We investigated social learning strategies using a simple problem-solving task in which participants search a complex space, and each can view and imitate others' solutions. Results showed that participants combined multiple sources of information to guide learning, including payoffs of peers' solutions, popularity of solution elements among peers, similarity of peers' solutions to their own, and relative payoffs from (...)
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  28.  3
    Die Relation in der Philosophie der Stoiker.Rudolf Löbl (ed.) - 1986 - Würzburg: Könighausen & Naumann.
  29. Politics and the social imaginary : the problem of the state - and the problem of modernity.Wolfgang Knöbl - 2023 - In Ľubomír Dunaj, Jeremy Smith & Kurt Cihan Murat Mertel (eds.), Civilization, modernity, and critique: engaging Jóhann P. Árnason's macro-social theory. New York, NY: Routledge, Taylor & Francis Group.
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  30. Is priming independent of procedural learning.Bl Schwartz, S. Hashtroudi & J. Smith - 1989 - Bulletin of the Psychonomic Society 27 (6):504-504.
  31.  26
    7 Reason and the practice of science.Thomas E. Wartenberg - 1992 - In Paul Guyer (ed.), The Cambridge companion to Kant. New York: Cambridge University Press. pp. 3--228.
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  32. Du désordre à l'ordre: le rôle de la violence dans Horace in The Existential Coordinates of the Human Condition: Poetic, Epic, Tragic. The Literary Genre.Bl Murphy - 1984 - Analecta Husserliana 18:435-447.
     
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  33. Jaina Inscriptions of Khajuraho.Bl Nagarch - 2002 - In Hīrālāla Jaina, Dharmacandra Jaina & R. K. Sharma (eds.), Jaina Philosophy, Art & Science in Indian Culture. Sharada Pub. House. pp. 1--69.
     
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  34. Thomas Reid's inquiry and essays.Thomas Reid - 1863 - Indianapolis: Bobbs-Merrill. Edited by Keith Lehrer & Ronald E. Beanblossom.
    INTRODUCTION Although the writings of Thomas Reid are very fertile and interesting, his life is biographically barren in comparison to such seventeenth - and ...
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  35.  2
    A Study of Sophoclean Drama.Herbert Musurillo & G. M. Kirkwood - 1959 - American Journal of Philology 80 (4):445.
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  36.  45
    What do you mean I wasn't cheating? Testing the concept of cheating through a case of failed doping.Ken Kirkwood - 2014 - Sport, Ethics and Philosophy 8 (1):57-64.
    Using a case of intended but failed doping, the author seeks to answer the question of if an agent cheated when they intended to but failed in the case of doping due to inert, counterfeit drugs. The examination looks at the case using the concept of cheating and concludes by dividing the results of cheating into primary and secondary effects.
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  37.  86
    The nature of art: an anthology.Thomas E. Wartenberg (ed.) - 2002 - Fort Worth: Harcourt College.
    THE NATURE OF ART is a collection of 29 seminal, historically-organized readings that are focused on a basic philosophical question: What is Art? Including writings from the Western tradition'both Continental and Analytic traditions'as well as non-Western, minority, and feminist writings, this volume provides students with a rich set of resources to explore this matter both broadly and deeply. Introductions to each reading situate the selection amidst each respective thinker's body of work and the greater philosophical context in which the remarks (...)
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  38.  4
    Right and wrong: a practical introduction to ethics.Thomas I. White - 2017 - Hoboken, NJ: Wiley-Blackwell.
    The newly updated Right and Wrong 2nd Edition is an accessible introduction to the major traditions in western philosophical ethics, written in a lively and engaging style. It is designed for entry-level ethics courses and includes real-life ethical scenarios chosen to appeal directly to students. Greatly expanded and improved, this successful text introduces students to the major ethical traditions, and provides a simple methodology for resolving ethical dilemmas Treats teleological and deontological approaches to ethics as the two most important traditions, (...)
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  39.  3
    What Kind of Beings are Dolphins?Thomas I. White - 2007 - In In Defense of Dolphins. Oxford, UK: Blackwell. pp. 155–184.
    This chapter contains section titled: Personhood: A Start Are Dolphins Persons? Language and the Hand Personhood Redefined Conclusion: What Kind of Beings Are Dolphins?
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  40. Can E-Sport Gamers Permissibly Engage with Off-Limits Virtual Wrongdoings?Thomas Montefiore & Paul Formosa - 2023 - Philosophy and Technology 36 (4):1-3.
    David Ekdahl (2023), in a constructive and thoughtful commentary, outlines both points of agreement with and suggestions for further research arising from our paper ‘Crossing the Fictional Line: Moral Graveness, the Gamer’s Dilemma, and the Paradox of Fictionally Going Too Far’ (Montefiore & Formosa, 2023).
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  41. Intuition and Judgment: How Not to Think about the Singularity of Intuition.Thomas Land - 2013 - In Stefano Bacin, Alfredo Ferrarin, Claudio La Rocca & Margit Ruffing (eds.), Kant und die Philosophie in weltbürgerlicher Absicht. Akten des XI. Internationalen Kant-Kongresses. Boston: de Gruyter. pp. vol. 2, 221-231.
    According to a widely held view, a Kantian intuition functions like a singular term. I argue that this view is false. Its apparent plausibility, both textual and philosophical, rests on attributing to Kant a Fregean conception of judgment. I show that Kant does not hold a Fregean conception of judgment and argue that, as a consequence, intuition cannot be understood on analogy with singular terms.
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  42.  52
    Caring about morality: philosophical perspectives in moral psychology.Thomas E. Wren - 1991 - Cambridge: MIT Press.
    In this book Thomas Wren uncovers and assesses the largely hidden philosophical assumptions about human motivation that have shaped contemporary psychological ...
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  43.  19
    Detachment: essays on the limits of relational thinking.Thomas Yarrow, Matei Candea, Catherine Trundle & Jo Cook (eds.) - 2015 - Manchester: Manchester University Press.
    This interdisciplinary volume questions one of the most fundamental tenets of social theory by focusing on detachment, an important but neglected aspect of social life. Going against the grain of recent theoretical celebrations of engagement, this book challenges us to re-think the relational basis of social theory. In so, doing it brings to light the productive aspects of disconnection, distance and detachment. Rather than treating detachment simply as the moral inversion of compassion and engagement, the volume brings together empirical studies (...)
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  44. Nietzsche’s Aristocratism Revisited.Thomas Fossen - 2008 - In Vasti Roodt & Herman W. Siemens (eds.), Nietzsche, Power and Politics: Rethinking Nietzsche's Legacy for Political Thought. De Gruyter. pp. 299-318.
  45.  3
    Geist und Gehirn: das Leib-Seele-Problem in der aktuellen Diskussion.Thomas Zoglauer - 1998 - Göttingen: Vandenhoeck & Ruprecht.
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  46.  17
    The Technological Fact of Counterfactuals.Jeffrey West Kirkwood - 2018 - Zeitschrift für Medien- Und Kulturforschung 9 (1):14-33.
    Optical media were instrumental in transforming the conception of facts, objectivity, and the »real.« This paper considers their role in structuring understandings of counterfactuals and states that could not be real. By returning to Ernst Mach’s photographic ballistics experiments, writing on thought experiments (a term he coined), and his dispute with Max Planck about the nature of the Weltbild, the article shows that, despite his legacy as a positivist, Mach’s epistemology of mechanical images opened a legitimate space of indeterminacy, contingency, (...)
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  47.  12
    Pindar's Ravens ( Olymp. 2. 87).G. M. Kirkwood - 1981 - Classical Quarterly 31 (02):240-.
    A problem in the text of Pindar, the interpretation of λαρετον, O. 2. 87, seems to be vanishing, swept away by a remarkable consensus of recent criticism, a consensus the more remarkable in that it accepts a false solution to a genuine difficulty. This article has two purposes, the first and more important of which is to argue that the currently prevailing answer is manifestly wrong, the second to offer evidence in support of a different approach. Simply read γαρυτων, recent (...)
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  48.  40
    The Comparative reception of Darwinism.Thomas F. Glick (ed.) - 1974 - Chicago: University of Chicago Press.
    The reaction to Darwin's Origin of Species varied in many countries according to the roles played by national scientific institutions and traditions and the attitudes of religious and political groups. The contributors to this volume, including M. J. S. Hodge, David Hull, and Roberto Moreno, gathered in 1972 at an international conference on the comparative reception of Darwinism. Their essays look at early pro- and anti-Darwinism arguments, and three additional comparative essays and appendices add a larger perspective. For this paperback (...)
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  49.  9
    Big ideas for little kids: teaching philosophy through children's literature.Thomas E. Wartenberg - 2014 - Lanham: Rowman & Littlefield Publishers.
    Big Ideas for Little Kids includes everything a teacher, a parent, or a college student needs to teach philosophy to elementary school children from picture books. Written in a clear and accessible style, the book explains why it is important to allow young children access to philosophy during primary-school education. Wartenberg also gives advice on how to construct a "learner-centered" classroom, in which children discuss philosophical issues with one another as they respond to open-ended questions by saying whether they agree (...)
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  50. Heidegger.Thomas E. Wartenberg - 2000 - In Berys Nigel Gaut & Dominic Lopes (eds.), The Routledge Companion to Aesthetics. Routledge.
     
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